GO:0034098 cellular_component VCP-NPL4-UFD1 AAA ATPase complex
| PAG Title | GO:0034098 cellular_component VCP-NPL4-UFD1 AAA ATPase complex |
| PAG ID | TAX022305 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry). |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 827 |
| Information Content | Rich |
| Other IDs | GO:0034098 |
| Base PAG ID | TAX022305 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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